Bioactive Vascular Implants: Stents and Bypass Grafts

Synopsis of project aims

This project develops bioactive vascular implants, including stents and bypass grafts, designed to improve endothelial integration, long-term patency, and functional performance.
It targets limitations of current implants, including thrombosis, restenosis, and poor tissue compatibility.

Approach

  • Design of hybrid biomaterials with controlled degradation and mechanics  
  • Development of drug-eluting stents and biomimetic grafts  
  • Integration of bioactive functionalities (anti-thrombotic, anti-inflammatory, antibacterial)  
  • Use of volumetric bioprinting, simulation, and perfusion systems for optimization  

Why This Matters

Existing vascular implants fail to replicate native vessel biology. This project enables next-generation implants that support endothelialization, reduce complications, and improve long-term clinical outcomes.

Project Team:

Jagoda Litowczenko-Cybulska

San Seint Seint Aye

MSc Urszula Zgórzyńska

MSc Julia Góral-Kucińska

Marta Przymuszałą

Roy Siegelmann  

Tolga Durak